What literature will do to you. I found it on the pinterest board Ludicrous Vintage Ads, which are a lot of fun when they aren't completely enraging.
Update! Here is some more information about it, from the Library of Congress. This image seems to be a variation of an illustration from a book called Social Purity, by one John W. Gibson, published in 1903.
Here is the original (?) image with the central text still intact, which reveals that the girl is reading the novel Sapho.